The treatment of acne, as with so many other medical disorders, has circled back on itself over the last few decades. Years ago, acne treatment depended upon “physical modalities,” such as scrubbing with harsh soaps, ultraviolet light, low-dose X-ray sessions, and dietary changes. Prescription medicines, both topical and internal, revolutionized acne therapy with great success, culminating with Accutane in the '80s, which is still by far the most effective medical agent for moderate to severe or stubborn acne. 

This powerful medication, known generically as isotretinoin, works by shrinking the oil glands and reducing inflammation, often producing long-lasting remission in patients who had previously struggled with persistent breakouts. However, it is accompanied by significant potential side effects, including dry skin, sun sensitivity, and, in rare cases, more severe concerns like depression, leading many patients to seek alternative solutions.